KMID : 0359720080260010055
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Journal of the Korean Neurological Association 2008 Volume.26 No. 1 p.55 ~ p.58
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Two Cases of Delayed Post-radiation Lower Cranial Nerve Palsies
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Park Hyung-Jun
Kwon Ki-Han Min Yang-Ki Suh Bum-Chun Shim Dong-Suk Kim Seung-Min Sunwoo Il-Nam
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Abstract
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Radiation-induced lower cranial neuropathy shows a clinical presentation similar to tumor recurrence or amyotrophic lateral sclerosis. We experienced two patients with bulbar palsies several years after radiotherapy for nasopharyngeal cancer. Brain magnetic resonance imaging showed no evidence of tumor recurrence. Electrophysiologic studies demonstrated mild denervation changes and myokymic discharges in muscles innervated by cranial nerves. Bulbar palsies progressed for 1 year then became stable. We emphasize the importance of myokymic discharges in the differential diagnosis of radiation-induced cranial neuropathy as radiation plexopathies.
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KEYWORD
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Radiation, Cranial nerve disease, Myokymia
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